Nael M Mostafa Selected Research

Adalimumab (Humira)

11/2022	Bridging Fixed Dose to Body Weight-based Regimen of Adalimumab in Paediatric Ulcerative Colitis Using a Pharmacometric Modelling Approach: Case Study with the Phase 3 ENVISION I Trial.
1/2022	Higher vs Standard Adalimumab Induction and Maintenance Dosing Regimens for Treatment of Ulcerative Colitis: SERENE UC Trial Results.
1/2022	Higher vs Standard Adalimumab Induction Dosing Regimens and Two Maintenance Strategies: Randomized SERENE CD Trial Results.
1/2021	Efficacy and safety of adalimumab in paediatric patients with moderate-to-severe ulcerative colitis (ENVISION I): a randomised, controlled, phase 3 study.
1/2020	A Genetic Variant in the BCL2 Gene Associates with Adalimumab Response in Hidradenitis Suppurativa Clinical Trials and Regulates Expression of BCL2.
1/2019	The effects of concomitant immunomodulators on the pharmacokinetics, efficacy and safety of adalimumab in paediatric patients with Crohn's disease: a post hoc analysis.
7/2018	Efficacy and Safety of Dose Escalation to Adalimumab 80 mg Every Other Week in Japanese Patients with Crohn's Disease Who Lost Response to Maintenance Therapy.
1/2018	Identification of HLA-DRB1 association to adalimumab immunogenicity.
1/2018	Efficacy and safety of continuing versus withdrawing adalimumab therapy in maintaining remission in patients with non-radiographic axial spondyloarthritis (ABILITY-3): a multicentre, randomised, double-blind study.
8/2016	Two Phase 3 Trials of Adalimumab for Hidradenitis Suppurativa.

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Nael M Mostafa Research Topics

Disease

8	Pain (Aches) 01/2022 - 08/2016
7	Leiomyoma (Uterine Fibroids) 12/2022 - 10/2018
7	Endometriosis 01/2022 - 10/2018
6	Menorrhagia 12/2022 - 10/2018
6	Crohn Disease (Crohn's Disease) 01/2022 - 11/2014
4	Ulcerative Colitis 11/2022 - 02/2014
3	Body Weight (Weight, Body) 11/2022 - 07/2014
3	Hidradenitis Suppurativa 01/2020 - 08/2016
2	Bone Resorption 01/2021 - 11/2020
2	Neoplasms (Cancer) 04/2015 - 09/2014
1	Osteoporotic Fractures 12/2022
1	Bone Fractures (Bone Fracture) 12/2022
1	Inflammation (Inflammations) 01/2022
1	HIV Infections (HIV Infection) 12/2021
1	Pelvic Pain 01/2020
1	Dysmenorrhea (Menstrual Pain) 01/2020
1	Infections 01/2019
1	Diabetic Nephropathies (Diabetic Nephropathy) 01/2018
1	Axial Spondyloarthritis 01/2018
1	Non-Radiographic Axial Spondyloarthritis 01/2018
1	Albuminuria 01/2018
1	Rheumatoid Arthritis 01/2018
1	Type 2 Diabetes Mellitus (MODY) 01/2018
1	Edema (Dropsy) 01/2018
1	Kidney Diseases (Kidney Disease) 01/2018
1	Nasopharyngitis 01/2018
1	Respiratory Tract Infections (Respiratory Tract Infection) 01/2018
1	Ankylosing Spondylitis 01/2018
1	Hypokalemia 04/2015
1	Fatigue 04/2015
1	Brain Neoplasms (Brain Tumor) 04/2015
1	Nausea 04/2015
1	Hyponatremia 04/2015
1	Precocious Puberty 07/2014
1	Hematologic Neoplasms (Hematological Malignancy) 05/2014
1	Prostatic Neoplasms (Prostate Cancer) 01/2014

Drug/Important Bio-Agent (IBA)

14	Adalimumab (Humira)FDA Link 11/2022 - 02/2014
9	elagolixIBA 12/2022 - 10/2018
6	LHRH Receptors (Gonadotropin-Releasing Hormone Receptor)IBA 12/2022 - 10/2018
4	Estradiol (Delestrogen)FDA LinkGeneric 12/2022 - 01/2020
4	Norethindrone Acetate (Norlutate)FDA LinkGeneric 12/2022 - 01/2020
3	veliparibIBA 04/2015 - 05/2014
2	Pharmaceutical PreparationsIBA 12/2022 - 01/2022
2	Peptides (Polypeptides)IBA 01/2022 - 10/2018
2	Gonadotropin-Releasing Hormone (GnRH)FDA Link 01/2020 - 10/2018
2	AtrasentanIBA 01/2018 - 01/2018
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2016 - 02/2014
2	Leuprolide (Lupron)FDA LinkGeneric 07/2014 - 01/2014
1	C-Reactive ProteinIBA 01/2022
1	AnionsIBA 01/2022
1	Antiviral Agents (Antivirals)IBA 12/2021
1	Lopinavir FDA Link 12/2021
1	Ritonavir (Norvir)FDA Link 12/2021
1	CalciumIBA 01/2021
1	Collagen Type I (Type I Collagen)IBA 01/2021
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2021
1	Biological ProductsIBA 01/2021
1	Immunosuppressive Agents (Immunosuppressants)IBA 01/2021
1	ProcollagenIBA 01/2021
1	GonadotropinsIBA 01/2020
1	Hormones (Hormone)IBA 01/2020
1	Immunologic Factors (Immunomodulators)IBA 01/2019
1	AlbuminsIBA 01/2018
1	CreatinineIBA 01/2018
1	HS 37IBA 01/2018
1	SodiumIBA 01/2018
1	Endothelin A ReceptorIBA 01/2018
1	6-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA 07/2014
1	Luteinizing Hormone (Lutropin)FDA LinkGeneric 07/2014
1	EnzymesIBA 05/2014
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 05/2014
1	Temozolomide (Temodar)FDA LinkGeneric 05/2014
1	Monoclonal AntibodiesIBA 02/2014

Therapy/Procedure

9	Therapeutics 12/2022 - 04/2016
1	Biological Therapy 01/2022
1	Duration of Therapy 01/2021
1	Radiotherapy 04/2015